Realizou-se estudo de preval\u00eancia de sibil\u00e2ncia em crian\u00e7as ind\u00edgenas Guarani hospitalizadas por infec\u00e7\u00e3o respirat\u00f3ria aguda baixa no Sul e Sudeste do Brasil, recrutadas a partir de um sistema de vigil\u00e2ncia implantado nas aldeias entre maio de 2007 e junho de 2008. Os dados foram extra\u00eddos por revis\u00e3o dos prontu\u00e1rios hospitalares. Estimaram-se raz\u00f5es de preval\u00eancia de sibil\u00e2ncia brutas e ajustadas segundo categorias das vari\u00e1veis explorat\u00f3rias, por regress\u00e3o de Poisson com ajuste para vari\u00e2ncia robusta. A preval\u00eancia de sibil\u00e2ncia foi de 58,1% (136\/234). Permaneceram significativamente associadas \u00e0 sibil\u00e2ncia no modelo final: faixa et\u00e1ria, inversamente associada (0-11 meses: refer\u00eancia; 24-35 meses: 0,63, IC95%: 0,40-0,99); interna\u00e7\u00e3o no outono (ver\u00e3o: refer\u00eancia; outono: 1,58, IC95%: 1,05-2,40); e sinais cl\u00ednicos de dispneia (1,41, IC95%: 1,09-1,83), tiragem (1,42, IC95%: 1,16-1,73) e estertor (1,43, IC95%: 1,09-1,87). Os resultados revelam elevada carga de morbidade por sibil\u00e2ncia e sugerem o fen\u00f3tipo de sibil\u00e2ncia persistente de in\u00edcio precoce, relacionada \u00e0 recorr\u00eancia de infec\u00e7\u00f5es respirat\u00f3rias virais.<\/p>\n
Abstract
\nPrevalence of wheezing was studied in Guarani indigenous children hospitalized for acute lower respiratory tract infections in Southern and Southeastern Brazil, recruited by a surveillanceroutine established in villages from May 2007 to June 2008. Data were obtained from hospital records. Crude and adjusted prevalence ratios forwheezing were estimated according to categories of target variables, using Poisson regression with robust variance. Prevalence of wheezing was 58.1% (136\/234). Risk factors that remained significantly associated with wheezing in the final model were: age bracket, inversely associated (0-11 months: reference; 24-35 months: 0.63, 95%CI: 0.40-0.99); hospitalization in the autumn (summer: reference; autumn: 1.58, 95%CI: 1.05-2.40); dyspnea (1.41, 95%CI: 1.09-1.83); chest indrawing (1.42, 95%CI: 1.16-1.73); crackles (1.43, 95%CI: 1.09-1.87). The results show a high disease burden related to wheezing and suggest the phenotype of early-onset persistent wheezing related to recurrence of viral respiratory infections.<\/p>\n","protected":false},"featured_media":5007,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","blocksy_meta":"","_links":{"self":[{"href":"https:\/\/patrimonio.art.br\/opocedoc\/wp-json\/wp\/v2\/tnc_col_4706_item\/5382"}],"collection":[{"href":"https:\/\/patrimonio.art.br\/opocedoc\/wp-json\/wp\/v2\/tnc_col_4706_item"}],"about":[{"href":"https:\/\/patrimonio.art.br\/opocedoc\/wp-json\/wp\/v2\/types\/tnc_col_4706_item"}],"replies":[{"embeddable":true,"href":"https:\/\/patrimonio.art.br\/opocedoc\/wp-json\/wp\/v2\/comments?post=5382"}],"version-history":[{"count":38,"href":"https:\/\/patrimonio.art.br\/opocedoc\/wp-json\/wp\/v2\/tnc_col_4706_item\/5382\/revisions"}],"predecessor-version":[{"id":23347,"href":"https:\/\/patrimonio.art.br\/opocedoc\/wp-json\/wp\/v2\/tnc_col_4706_item\/5382\/revisions\/23347"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/patrimonio.art.br\/opocedoc\/wp-json\/wp\/v2\/media\/5007"}],"wp:attachment":[{"href":"https:\/\/patrimonio.art.br\/opocedoc\/wp-json\/wp\/v2\/media?parent=5382"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}